itsp/enable is a SAP Parameter attribute which is used to control Enable the ITS / Web GUI kernel plugin information. This is available within R/3 SAP systems depending on the version and release level.
Below is the standard documentation available and a few details of the attributes values .
If this parameter is set to "1", the work processes try to activate the
ITS/Web GUI plug-in when starting up.
See SAP Parameter Documentation for full SAP documentation for this profile parameter.